What
is ViagraŽ?
ViagraŽ
is the first significant oral medication for
the treatment of Erectile Dysfunction (ED). The medicine was
originally developed as a cardiovascular medicine designed to
improve blood flow in the vessels of the heart. However, during
initial studies the medication was found to have a profound side
effect. Individuals began to report a remarkable difference in
their ability to achieve and maintain an erection. Viagra is the
most recommend male erection enhancement drug by doctors
worldwide.
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How does ViagraŽ work?
ViagraŽ
is dispensed as a pill and ingested orally. Approximately 30-60
minutes later the drug is absorbed in the bloodstream. ViagraŽ
then functions as an inhibitor to an enzyme called phosphodiesterase
type (PDE5) which is found primarily in the penis. By inhibiting
PDE5, smooth muscle in the penis remains relaxed for a longer
period. This allows for increased blood flow into the cavernous
tissue of the penis thereby generating a significantly enhanced erection. ViagraŽ is
unique in that it increases a natural occurring process, therefore,
only through sexual stimulation will an erection occur.
What
is the appropriate dose of Viagra?
The
standard dose is 50mg one hour prior to sexual activity. However,
if you are older than age 65 or have a serious kidney or liver
disease some physicians will recommend starting with the minimal
dose of 25mg. ViagraŽ should not be taken more than once per any
24-hour period and doses should not exceed 100mg. The half-life
of ViagraŽ, the time the drug remains effective after ingestion,
is approximately four hours.
What clinical studies have
been done?
ViagraŽ
was administered to more than 3000 patients (age 19-87 years)
with (ED) of various etiologies (organic, psychogenic or mixed)
with a mean duration of 5 years. ViagraŽ demonstrated statistically
significant improvement as compared to a placebo in all studies.
In one particular study concerning the frequency of successful
penetration during sexual activity and maintaining erection after
penetration, 83% of these patients reported an improved erection
on ViagraŽ verses 12% on a placebo medication.
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How much time must surpass
before ViagraŽ is effective?
Viagra is rapidly absorbed.
Maximum observed plasma concentrations are reached within 30 to
120 minutes (median time 60 minutes) of oral dosing on an empty
stomach. Note: when ViagraŽ is taken with a high fat content meal,
the rate of effectiveness can be significantly diminished.
What
happens if there is no sexual stimulation following the ingestion
of ViagraŽ?
ViagraŽ is naturally eliminated
from your body in a few hours.
